Tube of Caspase1 (ICE) Substrate3 peptide, fluo
Peptides

Caspase 1 (ICE) Substrate 3f, fluorogenic - 5 mg

$186.00
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  • Cat.Number : AS-25285-5
  • Availability :
    In stock

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Caspase-1 substrate; AFC (7-amino-4-trifluoromethylcoumarin)-derived caspase substrates are widely used for the fluorimetric detection of various caspase activities. Cleavage of AFC peptides by caspases generate strongly fluorescent AFC that is monitored fluorimetrically at 500-510 nm with excitation of 370-390 nm.

Specifications

Chemistry
Sequence one letter code
  • Ac-WEHD-AFC
Sequence three letter code
  • Ac-Trp-Glu-His-Asp-AFC
CAS registry number
  • 210344-99-3
Molecular Formula
  • C38H37F3N8O11
Molecular Mass/ Weight
  • 838.7
Properties
Absorbance (nm)
  • 380
Emission (nm)
  • 500
Modification
Conjugation type
  • Fluorescent dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • ≥ 95%
Storage & stability
Form
  • Lyophilized
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Codes
Code Nacres
  • NA.26

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Citations

HMG-CoA reductase inhibitors activate caspase-1 in human monocytes depending on ATP release and P2X7 activation.

J Leukoc Biol . 2012 Nov 16 ; 93(2) 289 | DOI : 10.1189/jlb.0812409.

  • Y.H. Liao
  • et al